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Bispecific antibodies (BsAbs) pose inherent challenges in expression, often leading to issues such as aggregation, fragmentation, and the generation of diverse charge variants due to their complex structures. Consequently, optimizing the upstream process for BsAb production is imperative. This optimization involves meticulous steps aimed at refining the production process, ultimately enhancing both the yield and quality of the final product. |
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Bispecific antibodies (BsAbs) pose inherent challenges in expression, often leading to issues such as aggregation, fragmentation, and the generation of diverse charge variants due to their complex structures. Consequently, optimizing the upstream process for BsAb production is imperative. This optimization involves meticulous steps aimed at refining the production process, ultimately enhancing both the yield and quality of the final product. |
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